PICSI (Physiological ICSI)


What is PICSI?


Physiological intracytoplasmic sperm injection (PICSI) is a technique used to select sperm to use in Intracytoplasmic sperm injection (ICSI) treatment. It involves placing sperm with hyaluronic acid (HA), a natural compound found in the body. PICSI identifies sperm that can bind to HA and these sperm are selected for use in treatment.


In which patients is the PICSI technique indicated?

The PICSI technique is indicated for those couples in which the male has poor sperm quality, or who have previously undergone IVF with the ICSI technique and have not achieved the desired results.

  1. Men with high level of DNA fragmentation in their sperm.

  2. Cases of repeated abortion in which the cause is male or unknown.

  3. When there is low concentration and poor semen morphology.

  4. Cases in which there have been previous cycles with poor embryonic quality.


Dr. Puneet Arora is one of the best infertility specialists in Gurugram, India with a successful career of more than 20 years. Dr. Puneet is an expert in this field and is one of the best IVF specialist and Gynecologist in Delhi/NCR. – She may explain more about Blastocyst in case you wish to discuss further.